"Our team is engaged in the development of biomaterials based on hyaluronan derivatives that can be used as part of ATMP (Advanced Therapy Medicinal Products).
We are particularly interested in the development of hydrogels suitable for 3D cell culture, which can also serve as matrices for controlled release of biologically active substances. We also study physicochemical parameters of our developed materials in relation to effectiveness within their application and their biocompatibility.
We are directly involved in designing optimal methods of chemical modifications of hyaluronan, optimizing the viscoelastic properties of developed materials, studying the possibilities of cultivation of various types of cells in our hydrogels, and participating in in vivo design experiments to verify the functionality of newly designed products.Our group cooperates with a wide range of research departments and we are also intensively focusing on the transfer of new technologies into manufacturing practice.
Our scientists are actively involved in addressing a number of European projects under the Framework Programs for Research and Innovation:
Within these projects, we have the opportunity to work with top European scientific workplaces."
PharmDr. Martin Pravda Ph.D., Head of Tissue Engineering Team
Methods and technical background:
Equipment for characterization of the viscoelastic and mechanical properties
- Instron® electromechanical universal testing machine
- Rheometer
Equipment for characterization of chemical properties
- NMR, LC-MS, HPLC, FT-IR, TGA etc.
Equipment for life-science field
- Tissue cultivation or histology
- qRT-PCR
- DNA array
- Electrophoresis
- Western blotting
- Flow cytometry
- Fluorescence confocal microscopy
- Complete facilities for cultivation and histology
Key tasks and responsibilities:
- Development of hyaluronic acid-based hydrogel materials for the field of tissue engineering and regenerative medicine
- Development of materials for the treatment of articular cartilage and bone adhesives
- Development of materials for dentistry, cardiology or tissue augmentation
- Optimization of mechanical properties of developed materials
- Study of the influence of parameters of hyaluronic acid derivatives on these properties
- Optimization of material properties for their final use - the study of the stability of these materials etc.
What do we require?
- Tertiary education (Ph.D.) graduated in Chemistry of Materials, Physical Chemistry, Polymer Chemistry, Biopolymers, Consumer chemistry or similar fields
- Experience in a similar position necessary
- Excellent orientation in scientific literature
- Knowledge of English (minimal level B2)
- Good knowledge of PC work with MS Office programs
- Ability to work in a team
- Responsibility, independence, thoroughness
- Interest in solving complex and multidisciplinary tasks
What do we offer?
- Support of personal development and education
- Flexible working hours with the ability to maximize harmonization of work and personal activities
- Foreign business trips
- One week of extra holidays after one year (overall 5 weeks)
- Background of a stable company with a tradition of more than 25 years in world markets
- Subsidized catering inside the company
- Financial contributions for children's recreation
- Discount on company products
- Interest-free housing loans
- Assistance in obtaining accommodation and loans for the purchase of own housing
