- Do you have the ambition of developing your talents in the field of biopolymer chemistry while being part of a team that transforms a natural product (hyaluronic acid) into molecules with novel properties and the potential of improving biological and healing processes?
- Are you not afraid of developing your talents in fields other than chemistry, such as open-mindedly collaborating with colleagues from diverse disciplines and materializing innovative ideas in chemical structures with various properties?
- Do you want to become a team player who tackles daily challenges in order to reach collective goals?
- Do you have the patience and determination to learn what is necessary for the success of a new product?
- Our team would provide you with these exact opportunities. Through our achievements, we have been steadily contributing to the successful progress of our firm (see our team’s publications below).
- We are looking for a new researcher who will design and implement chemical modifications of hyaluronic acid to develop new materials with potential applications in medicine, cosmetics, and veterinary.
- Development of oligosaccharide- and polysaccharide-based materials.
- Optimisation of chemical processes leading to increased efficiency of the final product.
- Detailed chemical characterization of materials meeting the quality control requirements.
- Generating new ideas and their experimental verification.
- Coordination of projects from the development of derivatives to the promotion of business.
- Active participation in conferences, congresses, and educational events.
- Coordination of company activities.
- PhD in organic chemistry, synthesis or polymer chemistry.
- Extensive and proven experience in organic synthesis or in a similar position is welcome.
- Experience in spectral Interpretation (NMR, FTIR, UV-Vis, MS etc.).
- Excellent orientation in professional literature and the ability to analyse data and information.
- Creativity in experimental design, critical thinking, willingness to face the challenges and risks associated with innovative research.
- Thoroughness, responsibility, independence, and organizational skills.
- Knowledge of English language min. level B1, basic knowledge of Czech language or a willingness to learn the language.
- Good knowledge of PC and MS Office programs.
- Strong communication and teamwork skills.
- Excellent presentation skills.
What do we offer?
- The work environment in modern laboratories equipped with an integrated instrument park that allows all levels of analysis (from molecular structures to cellular processes).
- A culture that promotes creative thinking in problem-solving and optimizing a solution.
- Workflows based on teamwork and a synergic, multi-disciplinary approach.
- Above-average wage linked to individual performance.
- Flexible working hours with the ability to maximize the balance between work and personal activities.
- Subsidized corporate catering.
- Financial support for education and personal development.
- Assistance in accommodation and loans for purchase of own housing.
Publications derived from our work:
- Aligned nanofibres made of poly(3-hydroxybutyrate) grafted to hyaluronan for potential healthcare applications. Huerta-Ángeles G, Knotková K, Knotek P, Židek O, Brandejsová M, Pokorný M, Vagnerová H, Roy I, Velebný V., J Mater Sci Mater Med. 2018 Mar 15;29(3):32.
- Grafting of steroids to hyaluronan towards the design of delivery systems for antioxidants: The role of hydrophobic core. Huerta-Ángeles G, Brandejsová M, Novotný J, Kopecká K, Šógorková J, Šmejkalová D, Velebný V., Carbohydr Polym. 2018 Aug 1;193:383-392.
- An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects. Huerta-Ángeles G, Nešporová K, Ambrožová G, Kubala L, Velebný V., Front Bioeng Biotechnol. 2018 May 17;6:62. doi: 10.3389/fbioe.2018.00062. eCollection 2018. Review.
- Synthesis of graft copolymers based on hyaluronan and poly(3-hydroxyalkanoates). Huerta-Angeles G, Brandejsová M, Nigmatullin R, Kopecká K, Vágnerová H, Šmejkalová D, Roy I, Velebný V., Carbohydr Polym. 2017 Sep 1;171:220-228.
- Linolenic acid grafted hyaluronan: Process development, structural characterization, biological assessing, and stability studies. Huerta-Angeles G, Brandejsová M, Kulhánek J, Pavlík V, Šmejkalová D, Vágnerová H, Velebný V., Carbohydr Polym. 2016 Nov 5;152:815-824.
- Synthesis of photo-crosslinkable hyaluronan with tailored degree of substitution suitable for production of water resistant nanofibers. Huerta-Angeles G, Brandejsová M, Knotková K, Hermannová M, Moravcová M, Šmejkalová D, Velebný V., Carbohydr Polym. 2016 Feb 10;137:255-263.
- Novel synthetic method for the preparation of amphiphilic hyaluronan by means of aliphatic aromatic anhydrides. Huerta-Angeles G, Bobek M, Příkopová E, Šmejkalová D, Velebný V., Carbohydr Polym. 2014 Oct 13;111:883-91. doi: 10.1016/j.carbpol.2014.05.035.
- Reductive alkylation of hyaluronic acid for the synthesis of biocompatible hydrogels by click chemistry. Huerta-Angeles G, Němcová M, Příkopová E, Šmejkalová D, Pravda M, Kučera L, Velebný V., Carbohydr Polym. 2012 Nov 6;90(4):1704-11.
